pH-Responsive, Amphiphilic Core–Shell Supramolecular Polymer Brushes from Cyclic Peptide–Polymer Conjugates
نویسندگان
چکیده
منابع مشابه
Responsive Polymer Brushes
The review focuses on responsive/switching behavior of polymer brushes. The structure of the polymer brushes is analyzed in terms of the constitution and conformation of polymer chains. Responsive properties are widely discussed based on phase transition mechanisms in a controlled environment when changes are induced by solvent quality, temperature, concentration of ions, and interactions with ...
متن کاملpH-responsive polymer-drug conjugates: Design and progress.
Polymer-drug conjugates are becoming established as a shining platform for drug delivery. Incorporation of pH-responsive linker between drug and polymer is expected to realize triggered release of bioactive agents from conjugates in specific sites, either in mildly acidic extracellular matrices of tumor tissues or, after cellular internalization, in acidic endosomes and lysosomes. As an emergin...
متن کاملOptically responsive supramolecular polymer glasses
The reversible and dynamic nature of non-covalent interactions between the constituting building blocks renders many supramolecular polymers stimuli-responsive. This was previously exploited to create thermally and optically healable polymers, but it proved challenging to achieve high stiffness and good healability. Here we present a glass-forming supramolecular material that is based on a trif...
متن کاملGlucose-responsive polymer brushes for microcantilever sensing†‡
Glucose responsive polymer brushes were synthesized on gold substrates and microcantilever arrays. The response properties of these brushes were evaluated by exposing them to different glucose concentrations for a range of pH values. This work demonstrates the potential for polymer brush-functionalized micromechanical cantilevers as glucose detectors. Furthermore, the work demonstrates that sti...
متن کاملResponsive polymer brushes for controlled nanoparticle exposure.
We propose the design of a novel mixed polymer brush system that could act as a selective sensor with a distinct on-off switch. In the proposed system, a (single) nanoparticle (such as an antibody) is end-attached to a responsive chain, which is surrounded by a brush of nonresponsive chains. The collapse of the responsive chain leads to a protected state, where the nanoparticle is hidden in the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Macro Letters
سال: 2017
ISSN: 2161-1653,2161-1653
DOI: 10.1021/acsmacrolett.7b00728